Revivify Your Body

Clinical Study Citations


Chronic Fatigue: “The efficacy of hyperbaric oxygen therapy in the management of chronic fatigue syndrome.” Akarsu S, Tekin L, Ay H, Carli AB, Tok F, Simşek K, Kiralp MZ.

Bone Regeneration: “Hyperbaric Oxygen therapy effects on bone regeneration in Type 1 diabetes mellitus in rats.”  Dias PC, Limirio PHJO, Linhares CRB, Bergamini ML, Rocha FS, Morais RB, Balbi APC, Hiraki KRN, Dechichi P.

Brain Injury: “Oxygen-induced mitochondrial biogenesis in the rat hippocampus.”  Gutsaeva DR, Suliman HB, Carraway MS, Demchenko IT, Piantadosi CA. 

Brain Injury: “Protection of mitochondrial function and improvement in cognitive recovery in rats treated with hyperbaric oxygen following lateral fluid-percussion injury.” Zhou Z, Daugherty WP, Sun D, Levasseur JE, Altememi N, Hamm RJ, Rockswold GL, Bullock MR. 

Plastic Surgery Recovery: “Is There an Association Between Hyperbaric Oxygen Therapy and Improved Outcome of Deep Chemical Peeling? A Randomized Pilot Clinical Study.” Wiser I, Roni AS, Ziv E, Friedman M, Efraty S, Heller L, Landau M, Friedman T. 

Nerve-related Pain: “Hyperbaric oxygen treatment produces an antinociceptive response phase and inhibits astrocyte activation and inflammatory response in a rat model of neuropathic pain.” Zhao BS, Meng LX, Ding YY, Cao YY.” 

ATP and Energy Production: “Effects of hyperbaric oxygen on energy production and xanthine oxidase levels in striated muscle tissue of healthy rats.” Kurt B, Kurt Y, Karslioğlu Y, Topal T, Erdamar H, Korkmaz A, Türközkan N, Yaman H, Odabaşi Z, Günhan O. 

Pain Management: “Reduced antinociceptive responsiveness to hyperbaric oxygen in opioid-tolerant mice.” Zhang Y, Stolz PA, Shirachi DY, Quock RM. 

Inflammatory Pain: “Repetitive hyperbaric oxygen treatment attenuates complete Freund's adjuvant-induced pain and reduces glia-mediated neuroinflammation in the spinal cord.” Hui J, Zhang ZJ, Zhang X, Shen Y, Gao YJ. 

Pain Management: “Hyperbaric oxygen therapy attenuates neuropathic hyperalgesia in rats and idiopathic trigeminal neuralgia in patients.” Gu N, Niu JY, Liu WT, Sun YY, Liu S, Lv Y, Dong HL, Song XJ, Xiong LZ. 

Pain Management: “Hyperbaric oxygen treatment induces a 2-phase antinociceptive response of unusually long duration in mice.” Chung E, Zelinski LM, Ohgami Y, Shirachi DY, Quock RM. 

Pain Management: “Hyperbaric oxygenation therapy alleviates chronic constrictive injury-induced neuropathic pain and reduces tumor necrosis factor-alpha production.” Li F, Fang L, Huang S, Yang Z, Nandi J, Thomas S, Chen C, Camporesi E. 

Pain Management in Lieu of NSAIDS: “Hyperbaric oxygen treatment decreases inflammation and mechanical hypersensitivity in an animal model of inflammatory pain.” Wilson HD, Wilson JR, Fuchs PN. 

Stem Cell Generation: “Stem cell mobilization by hyperbaric oxygen.” Thom SR, Bhopale VM, Velazquez OC, Goldstein LJ, Thom LH, Buerk DG. 

Blood Vessel Creation: “Wound healing angiogenesis: the clinical implications of a simple mathematical model.” Flegg JA, Byrne HM, Flegg MB, McElwain DL. 

Brain Injury: “Attenuating inflammation but stimulating both angiogenesis and neurogenesis using hyperbaric oxygen in rats with traumatic brain injury.” Lin KC, Niu KC, Tsai KJ, Kuo JR, Wang LC, Chio CC, Chang CP. 

Stem Cell Generation: “Endothelial progenitor cell release into circulation is triggered by hyperoxia-induced increases in bone marrow nitric oxide.” Goldstein LJ, Gallagher KA, Bauer SM, Bauer RJ, Baireddy V, Liu ZJ, Buerk DG, Thom SR, Velazquez OC. 

Blood Vessel Creation: “Effects of hyperbaric oxygen on the osteogenic differentiation of mesenchymal stem cells.” Lin SS, Ueng SW, Niu CC, Yuan LJ, Yang CY, Chen WJ, Lee MS, Chen JK. 

Brain Injury due to Stroke: “Long course hyperbaric oxygen stimulates neurogenesis and attenuates inflammation after ischemic stroke.” Lee YS, Chio CC, Chang CP, Wang LC, Chiang PM, Niu KC, Tsai KJ. 

Stem Cell Generation for Ulcerative Colitis: “Hyperbaric oxygen therapy stimulates colonic stem cells and induces mucosal healing in patients with refractory ulcerative colitis: a prospective case series.” Bekheit M, Baddour N, Katri K, Taher Y, El Tobgy K, Mousa E. 

Bone Repair: “Effects of hyperbaric oxygen on the osteogenic differentiation of mesenchymal stem cells.” Lin SS, Ueng SW, Niu CC, Yuan LJ, Yang CY, Chen WJ, Lee MS, Chen JK. 

Muscle Healing and Regeneration: “Enhancement of satellite cell differentiation and functional recovery in injured skeletal muscle by hyperbaric oxygen treatment.” Horie M, Enomoto M, Shimoda M, Okawa A, Miyakawa S, Yagishita K. 

Liver Regeneration: “Effect of hyperbaric oxygen on liver regeneration in a rat model.” Tolentino EC, Castro e Silva O, Zucoloto S, Souza ME, Gomes MC, Sankarankutty AK, Oliveira GR, Feres O. 

CNS Disorders: "Hyperbaric oxygen therapy promotes neurogenesis: where do we stand?” Mu J, Krafft PR, Zhang JH. 

Brain Injury due to Stroke: “Delayed hyperbaric oxygen therapy promotes neurogenesis through reactive oxygen species/hypoxia-inducible factor-1α/β-catenin pathway in middle cerebral artery occlusion rats.” Hu Q, Liang X, Chen D, Chen Y, Doycheva D, Tang J, Tang J, Zhang JH. 

Anti-Oxidant Protection: “The effects of hyperbaric oxygen application against cholestatic oxidative stress and hepatic damage after bile duct ligation in rats.” Ayvaz S, Kanter M, Aksu B, Sahin SH, Uzun H, Erboga M, Pul M. 

Alzheimer’s: “Hyperbaric oxygen and Ginkgo Biloba extract inhibit Aβ25-35-induced toxicity and oxidative stress in vivo: a potential role in Alzheimer's disease.” Tian X, Wang J, Dai J, Yang L, Zhang L, Shen S, Huang P. 

Attenuation of Cognitive Decline: “Hyperbaric oxygen preconditioning attenuates postoperative cognitive impairment in aged rats.” Sun L, Xie K, Zhang C, Song R, Zhang H. 

Prevention of Altitude Sickness: “Amelioration of rCBF and PbtO2 following TBI at high altitude by hyperbaric oxygen pre-conditioning.” Hu S, Li F, Luo H, Xia Y, Zhang J, Hu R, Cui G, Meng H, Feng H.