Revivify Your Body

Clinical Study Citations

 CLINICAL STUDIES ON HYPERBARIC OXYGEN THERAPY

Chronic Fatigue: “The efficacy of hyperbaric oxygen therapy in the management of chronic fatigue syndrome.” Akarsu S, Tekin L, Ay H, Carli AB, Tok F, Simşek K, Kiralp MZ. https://www.ncbi.nlm.nih.gov/pubmed/23682549

Bone Regeneration: “Hyperbaric Oxygen therapy effects on bone regeneration in Type 1 diabetes mellitus in rats.”  Dias PC, Limirio PHJO, Linhares CRB, Bergamini ML, Rocha FS, Morais RB, Balbi APC, Hiraki KRN, Dechichi P. https://www.ncbi.nlm.nih.gov/pubmed/29378458

Brain Injury: “Oxygen-induced mitochondrial biogenesis in the rat hippocampus.”  Gutsaeva DR, Suliman HB, Carraway MS, Demchenko IT, Piantadosi CA. https://www.ncbi.nlm.nih.gov/pubmed/16298077 

Brain Injury: “Protection of mitochondrial function and improvement in cognitive recovery in rats treated with hyperbaric oxygen following lateral fluid-percussion injury.” Zhou Z, Daugherty WP, Sun D, Levasseur JE, Altememi N, Hamm RJ, Rockswold GL, Bullock MR. https://www.ncbi.nlm.nih.gov/pubmed/17432723 

Plastic Surgery Recovery: “Is There an Association Between Hyperbaric Oxygen Therapy and Improved Outcome of Deep Chemical Peeling? A Randomized Pilot Clinical Study.” Wiser I, Roni AS, Ziv E, Friedman M, Efraty S, Heller L, Landau M, Friedman T. https://www.ncbi.nlm.nih.gov/pubmed/30450343 

Nerve-related Pain: “Hyperbaric oxygen treatment produces an antinociceptive response phase and inhibits astrocyte activation and inflammatory response in a rat model of neuropathic pain.” Zhao BS, Meng LX, Ding YY, Cao YY.”  https://www.ncbi.nlm.nih.gov/pubmed/24390961 

ATP and Energy Production: “Effects of hyperbaric oxygen on energy production and xanthine oxidase levels in striated muscle tissue of healthy rats.” Kurt B, Kurt Y, Karslioğlu Y, Topal T, Erdamar H, Korkmaz A, Türközkan N, Yaman H, Odabaşi Z, Günhan O. https://www.ncbi.nlm.nih.gov/pubmed/18280739 

Pain Management: “Reduced antinociceptive responsiveness to hyperbaric oxygen in opioid-tolerant mice.” Zhang Y, Stolz PA, Shirachi DY, Quock RM. https://www.ncbi.nlm.nih.gov/pubmed/24390852 

Inflammatory Pain: “Repetitive hyperbaric oxygen treatment attenuates complete Freund's adjuvant-induced pain and reduces glia-mediated neuroinflammation in the spinal cord.” Hui J, Zhang ZJ, Zhang X, Shen Y, Gao YJ. https://www.ncbi.nlm.nih.gov/pubmed/23680474 

Pain Management: “Hyperbaric oxygen therapy attenuates neuropathic hyperalgesia in rats and idiopathic trigeminal neuralgia in patients.” Gu N, Niu JY, Liu WT, Sun YY, Liu S, Lv Y, Dong HL, Song XJ, Xiong LZ. https://www.ncbi.nlm.nih.gov/pubmed/22354664 

Pain Management: “Hyperbaric oxygen treatment induces a 2-phase antinociceptive response of unusually long duration in mice.” Chung E, Zelinski LM, Ohgami Y, Shirachi DY, Quock RM. https://www.ncbi.nlm.nih.gov/pubmed/20418186 

Pain Management: “Hyperbaric oxygenation therapy alleviates chronic constrictive injury-induced neuropathic pain and reduces tumor necrosis factor-alpha production.” Li F, Fang L, Huang S, Yang Z, Nandi J, Thomas S, Chen C, Camporesi E. https://www.ncbi.nlm.nih.gov/pubmed/21596875 

Pain Management in Lieu of NSAIDS: “Hyperbaric oxygen treatment decreases inflammation and mechanical hypersensitivity in an animal model of inflammatory pain.” Wilson HD, Wilson JR, Fuchs PN. https://www.ncbi.nlm.nih.gov/pubmed/16750177 

Stem Cell Generation: “Stem cell mobilization by hyperbaric oxygen.” Thom SR, Bhopale VM, Velazquez OC, Goldstein LJ, Thom LH, Buerk DG. https://www.ncbi.nlm.nih.gov/pubmed/16299259 

Blood Vessel Creation: “Wound healing angiogenesis: the clinical implications of a simple mathematical model.” Flegg JA, Byrne HM, Flegg MB, McElwain DL. https://www.ncbi.nlm.nih.gov/pubmed/22326476 

Brain Injury: “Attenuating inflammation but stimulating both angiogenesis and neurogenesis using hyperbaric oxygen in rats with traumatic brain injury.” Lin KC, Niu KC, Tsai KJ, Kuo JR, Wang LC, Chio CC, Chang CP. https://www.ncbi.nlm.nih.gov/pubmed/22491549 

Stem Cell Generation: “Endothelial progenitor cell release into circulation is triggered by hyperoxia-induced increases in bone marrow nitric oxide.” Goldstein LJ, Gallagher KA, Bauer SM, Bauer RJ, Baireddy V, Liu ZJ, Buerk DG, Thom SR, Velazquez OC. https://www.ncbi.nlm.nih.gov/pubmed/16794267 

Blood Vessel Creation: “Effects of hyperbaric oxygen on the osteogenic differentiation of mesenchymal stem cells.” Lin SS, Ueng SW, Niu CC, Yuan LJ, Yang CY, Chen WJ, Lee MS, Chen JK. https://www.ncbi.nlm.nih.gov/pubmed/24568330 

Brain Injury due to Stroke: “Long course hyperbaric oxygen stimulates neurogenesis and attenuates inflammation after ischemic stroke.” Lee YS, Chio CC, Chang CP, Wang LC, Chiang PM, Niu KC, Tsai KJ. https://www.ncbi.nlm.nih.gov/pubmed/23533308 

Stem Cell Generation for Ulcerative Colitis: “Hyperbaric oxygen therapy stimulates colonic stem cells and induces mucosal healing in patients with refractory ulcerative colitis: a prospective case series.” Bekheit M, Baddour N, Katri K, Taher Y, El Tobgy K, Mousa E. https://www.ncbi.nlm.nih.gov/pubmed/27195128 

Bone Repair: “Effects of hyperbaric oxygen on the osteogenic differentiation of mesenchymal stem cells.” Lin SS, Ueng SW, Niu CC, Yuan LJ, Yang CY, Chen WJ, Lee MS, Chen JK. https://www.ncbi.nlm.nih.gov/pubmed/24568330 

Muscle Healing and Regeneration: “Enhancement of satellite cell differentiation and functional recovery in injured skeletal muscle by hyperbaric oxygen treatment.” Horie M, Enomoto M, Shimoda M, Okawa A, Miyakawa S, Yagishita K. https://www.ncbi.nlm.nih.gov/pubmed/24336879 

Liver Regeneration: “Effect of hyperbaric oxygen on liver regeneration in a rat model.” Tolentino EC, Castro e Silva O, Zucoloto S, Souza ME, Gomes MC, Sankarankutty AK, Oliveira GR, Feres O. https://www.ncbi.nlm.nih.gov/pubmed/16908331 

CNS Disorders: "Hyperbaric oxygen therapy promotes neurogenesis: where do we stand?” Mu J, Krafft PR, Zhang JH. https://www.ncbi.nlm.nih.gov/pubmed?term=PMID%3A%2022146131 

Brain Injury due to Stroke: “Delayed hyperbaric oxygen therapy promotes neurogenesis through reactive oxygen species/hypoxia-inducible factor-1α/β-catenin pathway in middle cerebral artery occlusion rats.” Hu Q, Liang X, Chen D, Chen Y, Doycheva D, Tang J, Tang J, Zhang JH. https://www.ncbi.nlm.nih.gov/pubmed/24757104 

Anti-Oxidant Protection: “The effects of hyperbaric oxygen application against cholestatic oxidative stress and hepatic damage after bile duct ligation in rats.” Ayvaz S, Kanter M, Aksu B, Sahin SH, Uzun H, Erboga M, Pul M. https://www.ncbi.nlm.nih.gov/pubmed/23462455 

Alzheimer’s: “Hyperbaric oxygen and Ginkgo Biloba extract inhibit Aβ25-35-induced toxicity and oxidative stress in vivo: a potential role in Alzheimer's disease.” Tian X, Wang J, Dai J, Yang L, Zhang L, Shen S, Huang P. https://www.ncbi.nlm.nih.gov/pubmed/22563944 

Attenuation of Cognitive Decline: “Hyperbaric oxygen preconditioning attenuates postoperative cognitive impairment in aged rats.” Sun L, Xie K, Zhang C, Song R, Zhang H. https://www.ncbi.nlm.nih.gov/pubmed/24870985 

Prevention of Altitude Sickness: “Amelioration of rCBF and PbtO2 following TBI at high altitude by hyperbaric oxygen pre-conditioning.” Hu S, Li F, Luo H, Xia Y, Zhang J, Hu R, Cui G, Meng H, Feng H. https://www.ncbi.nlm.nih.gov/pubmed/20158955